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Semaglutide reaches the maximum concentration in the body in one to three days after receiving a dose.[1] In the STEP clinical trials, patients on semaglutide reported weight loss within a few weeks of starting treatment.[1,4] The STEP 1 study included 1961 adult participants who were obese or overweight and had at least one weight-related condition.[4] Participants were randomly assigned to semaglutide or placebo with diet and exercise for 68 weeks

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Am J Physiol Gastrointest Liver Physiol (2007) 293(1):G21121.10.1152/ajpgi.00530.2006 94 TrivediSWiberSCEl-ZimaityHMBrubakerPL

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