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In July 2020, the patient self-ordered an intestinal antigenic permeability screen (Cyrex array), which showed increased levels of occludin/zonulin IgA, lipopolysaccharide (LPS) IgG, and IgA, indicating a leaky gut

People who have not seen success with other weight loss medications or treatments

In adults with obesity or overweight who have not achieved adequate results from lifestyle changes (like a reduced-calorie diet and increased physical activity) alone, the American Gastroenterological Association (AGA) recommends adding medication to the lifestyle changes rather than continuing with lifestyle modifications alone

In simple terms, it is a multiplier