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These receptors exist on pancreatic beta cells (which produce insulin), brain regions controlling appetite and reward, the stomaComparing Mechanisms of Actionch and intestines, liver, heart, and other tissues

This conversion helps to mitigate neuronal apoptosis and damage related to inflammation in mouse models of hypoxic-ischemic encephalopathy and traumatic brain injury (TBI) [108,109,110]

These findings suggest the potential neuroprotective effects of exenatide and indicate its utility as a biomarker of the treatment response in PD [98]