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Key safety considerations include: Always adhere to the recommended maximum daily dose of paracetamol (4 grams in 24 hours for adults with normal body weight, or 60 mg/kg/day for adults weighing less than 50 kg) Be aware that some combination products contain paracetamol, which could lead to inadvertent overdose Maintain adequate hydration, particularly as Wegovy may cause gastrointestinal side effects Monitor for any unusual symptoms when starting either medication Patients should feel reassured that taking paracetamol for occasional pain relief whilst on Wegovy is considered safe

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