MPP + treatment significantly reduces TIGAR expression in HT22 cells, downregulates NADPH, GPX4, and GSH levels, upregulates GSSG levels and the GSSG/GSH ratio, decreases adenosine triphosphate (ATP) production, and promotes neuronal ferroptosis, iron-dependent lipid peroxidation, and mitochondrial dysfunction, thereby exacerbating neuronal cytotoxicity
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Recalls & Warnings August 19, 2015 Soylent Meal Replacement Powder Reported to Contain Lead and Cadmium On August 13, 2015, an environmental-health watchdog group, As You Sow, filed a notice of intent to bring legal action against Soylent, a "meal replacement" powder, alleging violation of California's "Prop 65" Safe Drinking Water and Toxic Enforcement Act
