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FMN augments the antioxidant activity of porcine oocytes and early embryos To explore whether FMN promotes oocyte maturation and embryonic development in association with the antioxidant properties, we measured the levels of ROS and GSH, an endogenous antioxidant, in porcine MII stage oocytes and 4-cell stage embryos [a critical period for porcine early embryo zygotic genome activation (ZGA)] ( In MII stage oocytes, comparison to the control group, the FMN-treated groups fluorescence intensity of ROS was significantly lower (0.88 0.06), whereas the fluorescence intensity of GSH was significantly higher (1.24 0.06

10.1016/j.jdermsci.2023.06.008 158 NedoszytkoB.Sokoowska-WojdyoM.Ruckemann-DziurdziskaK.RoszkiewiczJ.NowickiR

Zitouni K, Nourooz-Zadeh J, Harry D, Kerry SM, Betteridge DJ, Cappuccio FP, et al

Grapes seed oil is also effective for reducing blemishes