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It was also linked to a 24 per cent reduction in heart disease-related deaths for the subgroup of people with pre-existing heart failure, and a 19 per cent reduction in deaths from any cause

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Clinical trials are underway to formally study whether GLP-1 agonists could treat alcohol use disorder, but no medications in this class are currently approved for that purpose

1 Introduction Myocarditis is a heterogeneous disease characterized by myocardial inflammation and cardiomyocyte injury ( The natural course of myocarditis exhibits a distinct stage-dependent progression ( Within this pathological context, alterations in cardiac energy metabolism have attracted increasing attention ( Experimental studies have consistently demonstrated that cardiomyocytes in myocarditis exhibit a metabolic shift from oxidative phosphorylation toward increased reliance on glycolysis, even under relatively oxygen-replete conditions ( In addition to cardiomyocytes, infiltrating immune cells within the myocardium undergo substantial metabolic remodeling