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2 Reductions have been seen in lesional skin and in bloodstream circulation as measured by gene expression analysis and enzyme-linked immunosorbent assay (ELISA)

Ethics statement The animal study was reviewed and approved, and all experimental work was executed in accordance with the guiding principles of the Institute of Laboratory Animal Resources, Commission on Life Sciences University, National Research Council (1996), accepted through the Ethical Committee of Riphah Institute of Pharmaceutical Sciences (Ref