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For details on how GLP-1 medications work and clinical data, see Independent Wellnesss overview: What Is GLP-1

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Adenosine is a naturally occurring vasodilator and is a cellular mediator of cardioprotective ischaemic conditioning (IC) [26] by directly activating phospholipase C and/or protein kinase C (PKC) via adenosine 1 receptors (A1R), which are widely present in myocardial tissue [27, 28]

10.1152/ajpregu.00128.2019 79 PriyadarshiniM.LaydenB