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For exogenous model, the oxp1 cells and oxp1 cells transformed with MCT-1and CD-147 were grown in complete synthetic medium overnight, WT cells (with or without empty vector) were grown on same condition as a control

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The prescribing provider maintains ultimate responsibility for determining the appropriateness of tirzepatide therapy for each individual patient

Results We observed that SEMA attenuates high-fat diet-induced metabolic alterations in mice fed with HFD for 24 weeks