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These studies highlighted several anti-cancer effects exerted by metformin on TC cells including: i) induction of cell death, ii) reduction of cell growth, iii) inhibition of the metastatic potential iv) modulation of chemokines in the tumor microenvironment, v) de-differentiating effects (increase in iodine up-take) (Klubo-Gwiezdzinska et al., 2013
Supernatants were diluted in sample buffer, heated at 95 C for 35 min, and subjected to denaturing (SDS) electrophoresis by loading 20 g protein/lane on precast 415% gradient polyacrylamide gels
L., Simonetti R
Medical History The presence of comorbidities such as type 2 diabetes, hypertension, hormonal imbalances or dyslipidemia may influence weight loss results
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