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Serious but rare adverse effects include pancreatitis, gallbladder disease, acute kidney injury (usually secondary to dehydration from gastrointestinal symptoms), and hypoglycemia when combined with insulin or sulfonylureas

Common Side Effects The majority of side effects associated with Ozempic and similar GLP-1 medications are gastrointestinal, directly related to their mechanism of slowing digestion

WIRED also reached out to a number of other telehealth companies offering oral semaglutide and tirzepatide, looking for more information about how they source these medications and what clinical evidence they use to back up assertions of efficacy, including Strut, Henry Meds, Willow, Zealthy, and Ivy RX, none of which responded to repeated requests for comment

Most people begin to see results within a few weeks of starting treatment, with continued weight loss over months