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This severe derangement in membrane structure causes an influx of Ca 2+ ions, which induce the cross-linking of membrane proteins and activate an ion channel that leads to the efflux of K + and H 2 O

The presence of TG enhances the influx and accumulation of LDL in the tunica intima, where it is oxidized by ROS, and picked up by macrophages via scavenger receptor (SR) CD36 to produce foam cells [169,170,171]

10.1111/1541-4337.12204 211 TricaricoP

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