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New weight loss drugs are in development, but GLP-1 injections and oral tablets remain the main options

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To view a copy of this license, visit About this article Cite this article Benedict, C., Barclay, J., Ott, V

Corticosteroids promote: Fat redistribution , causing central (truncal) obesity and the characteristic "cushingoid" appearance with prolonged use Fluid retention , leading to weight gain that may not reflect true fat accumulation but can be discouraging Muscle protein breakdown , reducing lean body mass and potentially lowering metabolic rate Insulin resistance , making weight loss more difficult The magnitude of these effects is generally dose- and duration-dependent