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Also, CARN may have enhanced MTX distribution into cells, reducing its serum levels

WEDNESDAY, July 23, 2025 (HealthDay News) -- Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are associated with reduced type 2 diabetes mellitus (T2DM)-related dementia risk compared with metformin, according to a study published online July 22 in BMJ Open Diabetes Research & Care.Mingyang Sun, from the People's Hospital of Zhengzhou University in China, and colleagues conducted a retrospective cohort study using data from a global health research network between 2004 and 2024 to examine the comparative effectiveness of GLP-1 RAs and metformin in reducing dementia risk

Taddei S, Ghiadoni L, Virdis A, Versari D, Salvetti A

However, 24-h DFO treatment uniquely altered transcription initiation regulation, protein catabolic processes, proteasomal activity regulation, and proteasome activationdistinct from DHA (Supplementary Fig