It has a multitude of functions including the stimulation of insulin hormone which regulates blood sugar by storing energy, the inhibition of the ghrelin hormone which induces appetite, the stimulation of the sympathetic nervous system to increase energy expenditure and slow the movement of the gastrointestinal tract.[10] Below is a visual representation of the effect of the GLP-1 drug on a multitude of body systems.[13] Essentially, GLP-1 drugs like Ozempic, Wegovy, etc
Advanced additions (moderate evidence): Resveratrol or Pterostilbene (200mg or 100mg daily), Taurine (1-2g daily), Astaxanthin (6-12mg daily), Carnosine (1g daily for diabetics)
If SDN-1 controls glp-1 transcription through the putative TFAP2 motif, we would not expect to observe an additive effect when the glp-1prom mutant was combined with sdn-1 knockdown
PubMed Mester R, Toren P, Mizrachi I, et al