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For more information regarding the exchange of public health data using TEFCA, we refer readers to the TEFCA Public Health Exchange Purpose Implementation Standard Operating Procedure (SOP)

doi: 10.1038/srep24838 112 NastasiCCandelaMBonefeldCMGeislerCHansenMKrejsgaardTet al

Additionally, although the thiolactone form has not been unequivocally identified in vivo , homocysteine could undergo intracellular cyclization into homocysteine thiolactone, which could be a major by-product of impaired homocysteine metabolism (Jakubowski, 1997