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Moreover, an alternative pathway of cysteine catabolism, which is mediated by CDO1, has been shown to be inactive in NRF2-addicted cancer cells due to DNA methylation at the CDO1 locus (Kang et al

7F, G), confirming that palbociclib induced dependency on GPX4 in vivo

Previous studies regarding GLP-1 receptor agonists and animal models of substance use disorder have tended to focus on male subjects despite over 59% of the 871,854 people prescribed GLP-1 receptor agonists from 2011-2023 being women [16]