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We note, that while the C1831 descriptor was updated effective January 1, 2023, the anterior surgical approachthe surgical approach for which the aprevo Cervical ACDF System is indicatedhas been included in the category's descriptor since its establishment and, as previously noted, cervical-specific procedures using the anterior surgical approach have been reported with C1831 in the outpatient setting

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Its role in preventing megaloblastic anemia was established as early as the 1930s, and by the 1960s, folate supplementation was proposed as a preventive measure against neural tube defects ( NTDs )

Npj Soft Matter 1 (1), 4