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Understanding what to do when tirzepatide stops working or why you might not lose weight in the first four weeks on semaglutide can help determine whether a switch is truly needed or whether adjustments to the current medication might solve the problem

FDA Safety Warnings or Clinical Trial Findings on Tirzepatide As of 2024, the FDA has not issued a black box warning specific to Zepbound, but it shares the same class-wide warning found on other GLP-1 drugs like Wegovy and Ozempic: a potential link to thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)

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DEPENDENCY & CYCLING No dependency or addiction is associated with peptide use