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One enrolled vegan/vegetarian subject was later excluded as a result of reported nausea and a low BMI, 1 omnivorous subject declined the challenge after being enrolled and giving consent, 3 subjects enrolled in the antibiotic suppression arms did not tolerate the antibiotics (gastrointestinal distress) and were thus excluded from the study, and 2 subjects admitting noncompliance with daily l-carnitine supplementation were only included in baseline challenge studies

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The opening of the PTP facilitates the upregulation of pro-apoptotic members of the Bcl-2 family, such as Bax and Bad, thereby inducing apoptosis

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