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Naringin/ grapefruit Shown to increase GDNF in a rodent model of Parkinsons disease [70]

The investigators examined the influence of a high-FODMAP diet on mast cell activation, which can lead to leaky gut syndrome

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The decrease in MMP can lead to the opening of pores thus increasing mitochondrial membrane permeability (121), and a large amount of H+ pumped into the mitochondrial matrix causes a disruption of proton concentration on both sides of the mitochondrial membrane to inhibit ATP synthesis and accelerate ATP hydrolysis