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Despite the significant investigation, MDA has only been recognized as a signaling molecule in a few studies, such as regulation of islet glucose-stimulated insulin secretion (GSIS) (187) and gene expression of specificity protein-1 ( Sp1 ) in hepatic stellate cells (188)

In 2011, Jana et al

Another key role of glutathione is as an anti-oxidant and free radical scavenger role, particularly important in the mitochondria, where the catabolic conversion of nutrient substrates into carbon dioxide and water, with the concomitant recovery of chemical energy as ATP and of reductive power as NAD(P)H takes place

Liu K, Hua S, Song L