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Taken together, these pieces of evidence suggest that the biosynthesis rate of glutathione might be involved in nephrotoxicity by increasing cellular retention of Hg, altering the redox balance and leading to cytotoxicity 46,47 , possibly via mitochondria dysfunction by altering the ratio of reduced (GSH) to oxidized (GSSG) glutathione in this organelle 48,49

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L-Carnitine hydrochloride ( hereinafter L-carnitine) (#C0283) was purchased from Sigma Aldrich (St

Preclinical research models have explored its interactions with angiogenic signaling, tissue response pathways, and receptor-associated biological mechanisms in small-animal and in-vitro studies