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13, 20, 26, 27, 48, 70, 71, 72 They are actively taken up into the brain 73 and can affect diverse physiological processes such as cell signaling, 71 neurotransmitter synthesis and release, 70 mitochondrial function, 20 lipid metabolism, 13, 74 immune function, 75 cellcell interactions 76 and gene expression

It should be noted that while lymphoid cells remain viable in the circulatory system without anchoring to a rigid surface, they do not proliferate there

As a result, most standard oral peptide capsules or tablets deliver minimal systemic exposure

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