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They slow stomach emptying, reduce appetite, and may cause side effects such as nausea, vomiting, or diarrhea, all of which can contribute to dehydration
"Its modulation may reduce sexual desire in some patients." "Common adverse effects, such as nausea, fatigue or malaise, as well as psychological adjustment to rapid weight loss, can indirectly decrease sexual desire."
Microbiota transplantation studies A study found that when scientists put gut bacteria from obese people into mice without bacteria, the mice gained much more weight than those that received bacteria from lean individuals [8]