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Some providers and patients interpret this as the medication not working but its usually just the pharmacology
see Figure 3 for changes in individual participants), waist circumference (6.6 cm [95% CI, 9.1 to 4.2]), total cholesterol level (7.0% [95% CI, 11.7% to 2.1%]), very low-density lipoprotein cholesterol level (11.0% [95% CI, 18.5% to 2.7%]), triglyceride level (11.0% [95% CI, 18.9% to 2.2%]), HbA 1c level (0.2 percentage points [95% CI, 0.2 to 0.1]), fasting plasma glucose level (3.9 mg/dL [95% CI, 7.2 to 0.7]), and C-reactive protein level (37.2% [95% CI, 51.7% to 18.5%]) were significantly greater with semaglutide vs with liraglutide (Table 2