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doi: 10.1631/jzus.B2200590 40 VenancioVPCiprianoPAKimHAntunesLMTalcottSTMertens-TalcottSU
doi: 10.3389/fpls.2018.01836 Received 28 September 2018 Accepted 27 November 2018 Published 21 December 2018 Volume 9 - 2018 Edited by Stanislav Kopriva, Universitt zu Kln, Germany Reviewed by Aziz Aziz, Universit de Reims Champagne-Ardenne, France
Because healthy proliferating cells do not rely on sustained FOXO4p53 sequestration for survival, they are less affected in experimental models
5,6 For example, free radicals play a role in detoxification of xenobiotics by oxidizing enzymes, in killing of microorganisms by macrophages and cytotoxic lymphocytes, and in the generation of prostaglandins and leukotrienes, which activate oxygenases (e.g., cyclooxygenases and lipoxygenase) and thus act as modulators of the inflammatory response
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