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Berkes, J., Viswanathan, V

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4.5 Serine, glycine, and threonine Serine, glycine, and threonine are closely linked to one-carbon metabolism within the metabolic network and determine the metabolic module of one-carbon metabolism-nucleotide synthesis-methyl donor generation-redox homeostasis. Unlike arginine or tryptophan, which are more oriented toward regulation through the effector molecule/receptor signaling axis, these amino acids more commonly influence inflammation-related gene expression and epigenetic states by affecting processes such as nucleotide synthesis, NADPH supply, and methyl donor generation (63)

10.3389/fphar.2021.619103 169 HaranJ