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egg quality Elevations in estradiol, prostaglandins, HOXA10 expression, and prolactin, as well as progesterone resistance ( Immune and inflammatory factors Immune and inflammatory factors are thought to play key roles in the pathogenesis of infertility in patients with endometriosis, by reducing gamete quality and rates of gamete transport and implantation, and by increasing rates of pregnancy loss

Also, due to the immaturity detoxification systems (enzymes), the presence of mycotoxins in their body will take time to be detoxified, and elimination of mycotoxins may be decreased as their glomerular filtration rate is less than 40% compared to adults and the function of the renal tubules is less mature [45,46]

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An imbalance in Treg numbers can have deleterious effects by limiting antiviral effects of effector T cells and contributing to an excessively stimulated immune response in severely infected patients (128)