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Such buffering could for example be mediated by activation of the Nrf2-Keap1-ARE pathway, which has been shown to be increased after polyphenol supplementation which in turn induces the expression of phase II detoxifying enzymes, responsible for reducing endogenous toxic metabolites [65]

Follow a Balanced Diet: Incorporate foods rich in vitamins A, C, and E to support skin health

When used responsibly and consistently, they can be a useful addition to a thoughtful skincare and wellness routine, supporting brighter, healthier-looking skin over time rather than chasing instant results

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