Exome sequencing of ALS and rare-variant analyses identified loss-of-function mutations in TBK1 (encoding TANK-binding kinase 1) in 13 of 252 familial ALS pedigrees, but not in sporadic ALS (Freischmidt et al., 2015)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 8.Lutchmansingh F.K., Hsu J.W., Bennett F.I., Badaloo A.V., McFarlane-Anderson N., Gordon-Strachan G.M., Wright-Pascoe R.A., Jahoor F., Boyne M.S
The resulting AIE-activatable copolymer self-assembled into spherical PC-hyd-TPE micelles, which were loaded with DOX