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In addition, melatonin can modulate redox signaling pathways, such as Nrf2, and regulate the gene expression of antioxidant enzymes such as SOD, GPx, and CAT [26]

Nonetheless, further clinical trials are necessary to validate and confirm the efficacy and bioavailability of collagen-based supplements in diabetes management

Since DmGSTS1-1 was highly expressed in the flight muscle, the localization of the corresponding GST enzyme might provide a protective role against oxidative stress generated from mitochondrial respiration [128]

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