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Several medications are also approved for pediatric obesity, including liraglutide, semaglutide, tirzepatide, and phentermine-topiramate in adolescents 12 years, whereas setmelanotide is restricted to specific genetically confirmed monogenic or syndromic obesity disorders in patients as young as 2 years depending on the indication

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The watchdog also said these drugs must not be taken during pregnancy, while trying to get pregnant or while breastfeeding, as there was not enough safety data to know whether taking the medicine could cause harm to the baby