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If you're not seeing expected results by week 8, PlexusDx recommends reviewing adherence, meal composition (protein intake matters), and discussing whether a dose adjustment is needed

In human, GLUT9a is expressed in the basolateral membrane of proximal tubules of human kidney, whereas, GLUT9b is expressed at the apical membrane of the collecting duct (So and Thorens, 2010)

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MSNs can also be functionalized with targeting ligands, such as folic acid or antibodies, which can increase the specificity of the treatment by binding to specific receptors on the surface of cancer cells