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Interestingly, the methylation reactions are catalyzed by enzymes requiring vitamin B12 and folate as co-factors

For future work, we plan to include more biological replicates, measure GST enzyme activity and glutathione redox status after RNAi, test combined knockdown of both genes, examine expression in other pine hosts and nematode populations, identify upstream regulators, and identify the specific substrates of these two GSTs

It takes about 45 weeks of consistent dosing to reach steady-state blood levels

Acetylcysteine can help by reducing the viscosity of mucus, making it easier to clear out of the respiratory system