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While it can increase calorie use, it also raises nutritional needs

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The Metabolic Hormone Quadrant Heres a simplified breakdown of four major hormone systems involved in weight, energy, and glucose regulation: Why GLP-1 Isnt Enough for Everyone While GLP-1s have helped millions lose weight, some patients eventually: Plateau, even at high doses Struggle with hunger return between doses Experience glycemic or lipid rebound post-discontinuation Thats because GLP-1 only targets part of the equation