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Some peptides that upregulate the production of growth hormone (GH) by the pituitary, such as sermorelin (GRF 1-29), tesamorelin, and CJC-1295, can also lead to increased levels of GH's main anabolic mediator, insulin-like growth factor 1 (IGF-1)

doi: 10.1126/science.290.5493.985

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