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[7] Distinctly, topiramate may potentiate central nervous system depression when co-administered with alcohol, opioids, or benzodiazepines, necessitating cautious dose titration and patient education on operating machinery

Tumour Biol 39:1010428317691429 Lpez de la Oliva AR, Campos-Sandoval JA, Gmez-Garca MC et al (2020) Nuclear translocation of glutaminase GLS2 in human cancer cells associates with proliferation arrest and differentiation