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There were no language or time restrictions on the search, but we focused on articles published in the past 20 years to ensure the relevance and timeliness of the information

Although n-3 polyunsaturated fatty acids such as EPA and DHA are known to have anti-inflammatory and anti-cancer activity, their detailed mechanisms of action have not been fully understood

0.5, 5, 50 g/mL) in ICR mice is the only reviewed study providing clear histological evidence of cardiotoxicity, which proved to be dose-dependent and prominent at 50 g/mL