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Outcome trials reviewed

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Additionally, previous investigations have revealed that thyroid cancer is characterized by enhanced glucose uptake, as detected by 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET), along with reduced radioiodine uptake capability (Tran et al., 2016

The TRIUMPH-4 Phase 3 data provides the most current safety information: Nausea: 38.1% (9 mg) to 43.2% (12 mg) versus 10.7% placebo Diarrhea: 34.7% (9 mg) to 33.1% (12 mg) versus 13.4% placebo Constipation: 21.8% (9 mg) to 25.0% (12 mg) versus 8.7% placebo Vomiting: 20.4% (9 mg) to 20.9% (12 mg) versus 0% placebo Decreased appetite: 19.0% (9 mg) to 18.2% (12 mg) versus 9.4% placebo The pattern is clear