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But it can lead to uncomfortable constipation that requires active management

This matters because butyrate is one of the main compounds the body actually uses

16,17 Additionally, butyrate can enter the brain via systemic circulation, attenuate microglial activation and the release of pro-inflammatory cytokines, modulate inflammatory cytokines and signaling pathways in primary astrocyte cultures, and promote the synthesis of -aminobutyric acid (GABA), exerting anxiolytic and antidepressant effects

Under these circumstances, an investigation might reveal that the hose was defectively designed, which led to the build-up of pressure and the resulting explosion