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As we learn more about these emerging exposures, there are more markets willing to consider coverage for it

This review summarizes the current research findings by which GLP-1RAs treatment of diabetic osteoporosis, postmenopausal osteoporosis and glucocorticoid-induced osteoporosis and describes possible mechanisms, such as GLP-1R/MAPK signaling pathway, GLP-1R/PI3K/AKT signaling pathway and Wnt/-catenin pathway, that are associated with GLP-1RAs and osteoporosis

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Reduced glucose levels can also increase the production of ROS causing oxidation damage and interfere with signaling pathways and finally lead to apoptosis and necrosis [16] (Fig