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If you want a broader explanation of the mechanism behind GLP-1 medications, this GLP-1 explainer is a helpful companion read

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In a diet-induced steatohepatitis mouse model with fructose exposure, retatrutide was associated with changes in hepatic triglycerides, cholesterol levels, alanine aminotransferase, and inflammatory markers, providing a useful system for studying how tri-agonist signaling influences liver biology in experimentally induced steatotic states [7]