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The continued activation of C-fibers during recurrent migraine attacks and the ensuing activation of CGRP-related nociception maintain TVS sensitization, thereby promoting migraine chronicity (5, 30)

Over time, this leads to skin that looks firmer and more resilient

Transdermal patches are being tested and developed for different medical applications, making way for FDA-approved GLP-1 transdermal patches in the future

The slowdown came fast, steadily, and relentlessly, as seen in Intuitives subsequent quarterly commentary: Q323: In bariatrics, we continued to see double digit growth albeit at a modestly lower growth rate compared to Q2 Q423: We saw a continued deceleration in growth throughout 2023, likely the result of the uptake of GLP-1 drugs. Q124: Bariatric procedure growth continued to moderate and was flat year-over-year