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Men experiencing erectile dysfunction should undergo appropriate cardiovascular, metabolic, hormonal, and psychological assessment before considering investigational treatment options

Summary: Some patients taking Wegovy report emotional changes such as mood swings, tearfulness, or low mood, though current UK regulatory evidence does not confirm a direct causal link between GLP-1 receptor agonists and mood disorders

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Healthcare providers who choose to prescribe off-label dosing should document their clinical rationale, discuss the experimental nature of the approach with patients, and implement appropriate monitoring protocols to assess both safety and efficacy