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4 Immunopharmacological implications Physiological levels of ROS, which are present in all living organisms, can activate both signaling pathways such as MAPK and ERK and transcription factors such as NF-B (Sies and Jones, 2020

The expression of ZO-1, Occludin, SIRT1, STAT3, p-STAT3, RORt, IL-6, IL-1, TNF-, and -actin was examined using the method previously described ( 2.14 Statistical analysis Data are presented as the mean standard deviation