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The easiness of formation of such covalent bond depends on overall redox potential of environment as well as pH (at low pH the equilibrium is shifted to the reduced, -SH form, under more basic conditions the -SH group is more willing to be oxidized and replaced by -SR, where R is anything except for hydrogen)
10.1016/j.cbi.2013.09.020 41 CreutzenbergO.BellmannB.KorolewitzR.KochW.MangelsdorfI.TillmannT.et al (2012)
Using si-ACSL4 or RSG to inhibit ACSL4 can provide efficient defense against intestinal epithelial damage brought on by LPS (195)
Xu D,Gao Y,Yuan X,He B
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