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Data Extraction and Synthesis Relevant materials from various sources were carefully chosen and incorporated throughout the literature to ensure accuracy

Avoid harsh scrubs that can cause micro-tears and irritation

Gastrointestinal side effects were the most common adverse events

These dipeptides stimulate the metabolism, migration, and proliferation of fibroblasts and generate increased collagen and hyaluronic acid production.1214 There is a growing interest in hydrolyzed oral collagen supplements, especially in powder forms.15 The effects of hydrolyzed collagen supplementation on skin aging were evaluated in a systematic review and meta-analysis of 19 double-blind RCTs12 involving 1125 individuals