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Compound Overview Class of Compound: Peptide Mechanism of Action: PT-141 is an agonist of the melanocortin receptors, with high affinity for MC4R, the stimulation of which increases sexual desire and causes sexual arousal in both men and women Notable Studies: Also Known As: Bremelanotide, bremelanotide acetate, Rekynda, Vyleesi, CID9941379 Research Applications: Sexual funtion Male sexual arousal Anti-inflammatory action Risks: Injection-related side effects Temporarily increases blood pressure Not FDA approved to treat men

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Herein, the esterase-responsive polymeric nanoparticles (EsCu@NPs) are developed